Signatures of antagonistic pleiotropy in a bacterial flagellin epitope

Signatures of antagonistic pleiotropy in a bacterial flagellin epitope

Immune methods reply to “non-self” molecules termed microbe-associated molecular patterns (MAMPs). Microbial genes encoding MAMPs have adaptive features and are thus evolutionarily conserved. Within the presence of a number, these genes are maladaptive and drive antagonistic pleiotropy (AP) as a result of they promote microbe elimination by activating immune responses. The function AP performs in …

Signatures of antagonistic pleiotropy in a bacterial flagellin epitope Read More »