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Epitope and Paratope Mapping by HDX-MS Combined with SPR Elucidates the Difference in Bactericidal Activity of Two Anti-NadA Monoclonal Antibodies

Epitope and Paratope Mapping by HDX-MS Combined with SPR Elucidates the Difference in Bactericidal Activity of Two Anti-NadA Monoclonal Antibodies

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Characterization of antigen-antibody interactions is essential for understanding antibody-mediated safety towards pathogens, biopharmaceutical growth, in addition to analysis of the immune response put up vaccination. Bexsero is a multicomponent vaccine towards Neisseria meningitidis serogroup B through which one of many key vaccine antigens is Neisserial adhesin A (NadA), a trimeric coiled-coil protein. Two NadA-specific monoclonal antibodies (mAbs) […]

Epitope and Paratope Mapping by HDX-MS Combined with SPR Elucidates the Difference in Bactericidal Activity of Two Anti-NadA Monoclonal Antibodies Read More »

Identification of a novel protective human monoclonal antibody, LXY8, that targets the key neutralizing epitopes of staphylococcal enterotoxin B

Identification of a novel protective human monoclonal antibody, LXY8, that targets the key neutralizing epitopes of staphylococcal enterotoxin B

Antibodies, Assay Kits, Biology Cells, Blog, cDNA, Clia Kits, Culture Cells, Devices, DNA, DNA Templates, Elisa Kits, Enzymes, Equipments, Exosomes, Gels, Isotypes, Pcr Kits, Recombinant Proteins, Ria Kits, RNA, Test Kits, Vector & Virus, Western Blot /

Staphylococcal enterotoxin B (SEB), one of many exotoxins produced by Staphylococcus aureus, is the important thing toxin that causes poisoning reactions and poisonous shock syndrome. Within the present analysis work, a novel human antibody named LXY8 was screened from a human phage show antibody library, and LXY8 blocked the interplay between SEB and the T

Identification of a novel protective human monoclonal antibody, LXY8, that targets the key neutralizing epitopes of staphylococcal enterotoxin B Read More »

Development of multi-epitope peptide-based vaccines against SARS-CoV-2

Development of multi-epitope peptide-based vaccines against SARS-CoV-2

Antibodies, Assay Kits, Biology Cells, Blog, cDNA, Clia Kits, Culture Cells, Devices, DNA, Elisa Kits, Enzymes, Equipments, Exosomes, Gels, Isotypes, Medium & Serums, NATtrol, Particles, PCR, Pcr Kits, Recombinant Proteins, Ria Kits, RNA, Test Kits, Vector & Virus, Western Blot /

Extreme acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has precipitated a pandemic involving so excess of 32 million infections and 980,031 deaths. Efficient vaccines are urgently wanted to stop SARS-CoV-2 infections. No vaccines have but been accepted for licensure by regulatory businesses. Although host immune responses to SARS-CoV-2 infections are starting to be unravelled, efficient clearance

Development of multi-epitope peptide-based vaccines against SARS-CoV-2 Read More »